Acromegaly and gigantism are two medical conditions caused by an overproduction of growth hormone during adulthood and childhood, respectively. While both conditions result from an overproduction of growth hormone, there are some distinct features that differentiate them.
Acromegaly is a condition that affects adults and is caused by the overproduction of growth hormone after the body's growth plates have closed, usually in the early twenties. This condition is usually caused by a tumor in the pituitary gland. Symptoms of acromegaly include an enlarged jaw, large hands and feet, coarse facial features, protruding forehead, and thickening of the skin. Other symptoms may include headaches, vision problems, joint pain, fatigue, and increased sweating.
Gigantism is a condition that affects children and is caused by the overproduction of growth hormone before the body's growth plates have closed. This condition is usually caused by a tumor in the pituitary gland. Symptoms of gigantism include rapid growth, an enlarged jaw, large hands and feet, and thickening of the skin. Other symptoms may include headaches, vision problems, joint pain, fatigue, and increased sweating.
Both acromegaly and gigantism can be treated with medication, surgery, and/or radiation therapy. In some cases, lifestyle changes such as diet and exercise may be beneficial. It is important to seek medical attention if you suspect you or your child is suffering from either of these conditions.