Haemolytic disease is a condition caused by a defect in the red blood cells. This can cause anemia, jaundice, and other health problems. Clinical features of haemolytic disease include:
Anemia
Anemia is a common symptom of haemolytic disease. This is due to the destruction of red blood cells, which leads to a decrease in the number of red blood cells in the body. Symptoms of anemia include fatigue, shortness of breath, pale skin, and dizziness.
Jaundice
Jaundice is another common symptom of haemolytic disease. This is due to the buildup of bilirubin in the blood, which causes the skin and eyes to become yellow. Other symptoms of jaundice can include dark urine, light stools, and itching.
Enlarged Spleen
The spleen may become enlarged in haemolytic disease due to the destruction of red blood cells. This can cause abdominal pain, a feeling of fullness, and an increase in the size of the abdomen.
Kidney Damage
Kidney damage is a possible complication of haemolytic disease. This is due to the accumulation of waste products from the destruction of red blood cells in the kidneys. Symptoms of kidney damage include swelling of the feet and ankles, dark urine, and fatigue.
Blood Clotting Problems
Haemolytic disease can cause blood clotting problems due to the destruction of red blood cells. This can lead to an increased risk of bleeding and bruising.
Treatment
Treatment of haemolytic disease is aimed at reducing the destruction of red blood cells and managing any complications that may arise. Treatment may include blood transfusions, medications to reduce the destruction of red blood cells, and treatments to manage any complications.