Gigantism is a rare disorder that is most commonly caused by an abnormally high level of growth hormone in the body during childhood. It is characterized by an excessive growth of the body, including the head, hands, feet, and limbs. As a result, individuals with this disorder can reach heights of up to 8 feet tall or more.
The clinical features of gigantism vary depending on the cause, but some of the most common signs and symptoms include:
• Rapid and excessive growth: Individuals with gigantism experience an abnormal growth rate during childhood, which can lead to heights of over 8 feet tall.
• Enlarged hands, feet, and facial features: Individuals with gigantism may have abnormally large hands, feet, and facial features such as the nose, jaw, and forehead.
• Excessive body hair: Individuals with gigantism may have an abnormally large amount of body hair, especially on the face, chest, arms, and legs.
• Joint pain: Individuals with gigantism may experience joint pain as a result of their abnormal growth.
• Impaired vision: Individuals with gigantism may experience impaired vision due to an increased pressure in the skull.
• Organ dysfunction: Individuals with gigantism may experience organ dysfunction due to the pressure of their enlarged body on their internal organs.
• Cognitive impairment: Individuals with gigantism may experience cognitive impairment due to their enlarged brain size.
Gigantism can be diagnosed through a physical examination by a doctor. Blood tests and imaging tests such as X-rays and MRI scans may also be used to diagnose gigantism. Treatment for this disorder typically involves medications to reduce the amount of growth hormone in the body, as well as lifestyle modifications to reduce the risk of complications.