Yes, cortisol levels are typically high in those with acromegaly, a condition that results from an overproduction of growth hormone. This excess of growth hormone stimulates the adrenal glands to produce too much cortisol, a hormone involved in the body’s stress response.
As the body's stress hormone, cortisol is responsible for regulating a wide range of functions, including metabolism, immune system response, blood pressure, and other important bodily processes. It is also involved in the body's fight-or-flight response. When the body is stressed, cortisol is released to help the body respond appropriately.
In people with acromegaly, the pituitary gland produces too much growth hormone, which results in the overproduction of cortisol. This can lead to a variety of physical and psychological symptoms, including increased blood pressure, anxiety, fatigue, and weight gain.
In addition, high levels of cortisol can interfere with the body’s normal production of other hormones, such as testosterone and estrogen. This can lead to further complications, including infertility and irregular menstrual cycles.
Fortunately, there are treatments available for those with acromegaly. Medication can be used to reduce the amount of growth hormone being produced, which can help to reduce the levels of cortisol. Surgery is also available to remove the tumor that is causing the overproduction of growth hormone.
In conclusion, yes, cortisol levels are typically high in those with acromegaly. Fortunately, there are treatments available to help reduce the levels of cortisol and minimize the symptoms of this condition.