Alzheimer's disease is a progressive, degenerative disorder that affects the brain and results in impaired memory, thinking, and behavior. It is the most common form of dementia, accounting for up to 80% of all cases.
The exact cause of Alzheimer's disease is not yet known, but scientists believe that it is a combination of genetic and environmental factors that contribute to the onset of the disease. Studies have shown that there is a strong genetic component to Alzheimer's, with approximately 10-15% of cases being linked to a genetic mutation.
Inherited or genetic Alzheimer's is caused by a mutation in one of three genes: APP, PSEN1, or PSEN2. People who have inherited a mutation in one of these genes have a 50% chance of developing the disease. In addition, family members of people who have the mutation have a higher risk of developing Alzheimer's than the general population.
For most people, however, Alzheimer's is not inherited or genetic. It is believed that age, lifestyle, and environmental factors also play a role in the development of the disease. Factors such as head injuries, high blood pressure, diabetes, and obesity have been linked to an increased risk of developing Alzheimer's.
In conclusion, while some cases of Alzheimer's are inherited, the majority of cases are not. Age, lifestyle, and environmental factors can all influence the development of the disease. It is important to talk to your doctor if you are concerned about your risk of developing Alzheimer's.