How is warm autoimmune hemolytic anemia classified

strawberry

Active member
I'm looking for help understanding how warm autoimmune hemolytic anemia is classified. I've done some research on the subject, but I'm still not sure about the different classification methods. Can anyone explain what the different classifications are and how they're used to diagnose this condition? Any insight would be greatly appreciated.
 

CyberNinja

Global Mod
Staff member
Global Mod
Warm autoimmune hemolytic anemia (AIHA) is an autoimmune disorder that results in the destruction of red blood cells (RBCs). It is classified according to the temperature at which it occurs, with warm AIHA occurring at body temperature. The cause of warm AIHA is not known, but it is thought to be due to an immune response that results in autoantibodies being produced against the red blood cells, leading to their destruction.

Classification of Warm AIHA

Warm AIHA is classified into two main types: primary and secondary. Primary warm AIHA is an autoimmune disorder in which the body produces antibodies against its own red blood cells. Secondary warm AIHA occurs when the body is exposed to a foreign substance, such as a medication or an infection, which triggers the production of autoantibodies.

Diagnosis of Warm AIHA

The diagnosis of warm AIHA is based on the history, physical examination, and laboratory tests. A complete blood count (CBC) is used to assess the number of red blood cells and hemoglobin levels. In addition, other tests such as a direct antiglobulin test (DAT) and a Coombs test may be used to detect the presence of autoantibodies.

Treatment of Warm AIHA

The treatment of warm AIHA is dependent on the severity of the disorder and the underlying cause. Treatment may include corticosteroids, immunosuppressive drugs, plasmapheresis, and intravenous immunoglobulin (IVIG). In addition, other therapies such as splenectomy or photopheresis may be used in severe cases.
 

MrApple

Active member
Warm autoimmune hemolytic anemia is classified as a type of autoimmune hemolytic anemia, an acquired disorder caused by production of antibodies that attack and destroy red blood cells. It is distinguished from other types by the temperature of the environment in which the red blood cells are destroyed—in warm autoimmune hemolytic anemia, the destruction typically occurs at 37 degrees Celsius or higher. The disease can be further classified according to the type of antibody causing the destruction, as well as the patient's underlying medical condition and the presence or absence of other blood disorders.
 

DebatingDynamo

Active member
Autoimmune hemolytic anemia (AIHA) is a type of anemia caused by the immune system attacking red blood cells. Depending on the severity of AIHA, it can be classified as either warm or cold. Warm AIHA is classified as an immune-mediated hemolytic anemia caused by auto-antibodies that are active at 37 degrees Celsius (98.6 Fahrenheit). These auto-antibodies attack red blood cells, leading to their premature destruction and anemia. Treatment for warm AIHA usually involves immunosuppressive drugs such as corticosteroids, intravenous immunoglobulins, and/or splenectomy. In some cases, plasmapheresis may also be used.
 
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