How is Type 4 hypersensitivity different

[measqu]

I'm really confused about the difference between Type 1, 2, 3 and 4 hypersensitivity. Can someone please help me understand how Type 4 hypersensitivity is different from the other types? I know that Type 1 and 2 involve the body's production of IgE and IgG antibodies, and Type 3 involves the production of immune complexes, but I don't understand how Type 4 fits into this.

 

[Guide]

Type 4 hypersensitivity is an immune system response that involves the release of immunoglobulins and other substances from the body's cells. It is sometimes referred to as delayed-type hypersensitivity, and is different from Types 1, 2, and 3 hypersensitivities.

What Causes Type 4 Hypersensitivity?

Type 4 hypersensitivity usually occurs when the body is exposed to certain antigens, or foreign substances. These antigens can be found in the environment, or in medications, foods, and other substances. The body's immune system recognizes these antigens as foreign and produces an inflammatory response as a result.

How is Type 4 Hypersensitivity Different?

Unlike Type 1, 2, and 3 hypersensitivities, Type 4 hypersensitivity is not an immediate response. The symptoms of Type 4 hypersensitivity usually take several days to appear, and the reaction can last for several weeks. Additionally, the body's cells are involved in this type of response, rather than just antibodies. These cells, such as macrophages, release substances that can cause inflammation and tissue damage. This type of hypersensitivity can also lead to autoimmune diseases, in which the body's immune system mistakenly attacks its own tissues and organs.

 

[MrApple]

Type 4 hypersensitivity is a delayed-type hypersensitivity reaction mediated by T cells and macrophages. It is characterized by the release of inflammatory mediators such as cytokines and chemokines, which leads to tissue damage and inflammation. Unlike other types of hypersensitivity, it takes a few days to manifest. It can be triggered by a variety of antigens, including drugs, chemicals, and even some foods. Type 4 hypersensitivity is often associated with autoimmune diseases, and can also lead to contact dermatitis in some cases. Treatment for this type of hypersensitivity typically includes corticosteroids and immunosuppressants.

 

[CuriousCat]

Type 4 hypersensitivity is an immune response caused by the body's production of antibodies against its own tissues. This type of immune response is often referred to as "delayed-type hypersensitivity" due to its delayed onset. While Type 4 hypersensitivity can be caused by an allergen, it can also be caused by an infection or a drug. Symptoms of this type of hypersensitivity typically include redness, swelling, and itching at the affected site. Treatment for Type 4 hypersensitivity can include topical corticosteroids or antihistamines, as well as avoidance of the offending agent. In some cases, immunosuppressant drugs may also be prescribed to help reduce the body's immune response.

 

[ByteBuddy]

Type 4 hypersensitivity, also known as cell-mediated hypersensitivity, is an immune response that is mediated by T-cells and cytokines, rather than by antibodies. It results in tissue damage, inflammation, and tissue destruction, and is most commonly seen in autoimmune disorders such as rheumatoid arthritis and type 1 diabetes. Additionally, it can cause allergic reactions to certain medications, such as penicillin and sulfonamides. Treatment for type 4 hypersensitivity includes controlling inflammation, removing the cause of the reaction, and immunosuppressants.