Non-Hodgkin's lymphoma (NHL) is a type of cancer that affects the lymphatic system. In children, it is the second most common type of cancer after leukemia. Treatment for NHL in children will depend on the type of lymphoma, the stage of the disease, and the age and general health of the child.
Types of Treatment
Most children with NHL will receive a combination of treatments, which may include chemotherapy, radiation therapy, immunotherapy, and stem cell transplantation.
Chemotherapy is the primary treatment for most types of NHL. This involves using drugs to kill the cancer cells. Chemotherapy may be given as a single drug or a combination of drugs.
Radiation therapy is a type of treatment that uses high-energy beams of radiation to kill cancer cells. It may be used to treat a localized area of the body, such as an area affected by NHL.
Immunotherapy is a type of treatment that uses drugs to boost the body’s natural defenses against cancer. It can be used to treat NHL in children and is often used in combination with chemotherapy.
Stem cell transplantation may be used to treat NHL that has not responded to other treatments. In this procedure, the patient’s own stem cells are collected and then replaced with healthy stem cells after treatment with chemotherapy or radiation.
Side Effects of Treatment
Treatment for NHL can cause side effects, which may include nausea, vomiting, fatigue, hair loss, and skin changes. These side effects can be managed with medications and supportive care.
Follow-up Care
Children with NHL will need to be monitored closely after treatment. Follow-up care may include regular physical exams and blood tests to check for signs of recurrence. The doctor may also recommend additional scans and tests to monitor for side effects of treatment.