Myasthenia Gravis (MG) is an autoimmune disorder that causes muscle weakness and fatigue. Diagnosing MG can be a challenge as there are several tests that are used to confirm the diagnosis.
The first step in diagnosing MG is to perform a physical exam. During the physical exam, the doctor will examine the patient’s muscle strength, reflexes, and coordination. The doctor may also ask questions about the patient’s medical history, including any medications they are taking and their family history of autoimmune diseases.
The next step is to perform blood tests to check for levels of antibodies that may be associated with MG. These tests can also help rule out other conditions with similar symptoms, such as thyroid disease or multiple sclerosis.
The third step is to perform a nerve conduction study (NCS). During an NCS, electrodes are placed on the patient’s skin and electrical impulses are sent through the nerves. This test can help detect electrical abnormalities in the nerves, which can be a sign of MG.
The fourth step is to perform a single-fiber electromyography (SFEMG). During an SFEMG, very thin needles are inserted into the patient’s muscles and electrical activity is measured. This test can detect abnormal electrical activity in the muscles, which can be a sign of MG.
Finally, the fifth step is to perform a tensilon test. During this test, the patient is given an injection of a medicine called edrophonium. If the patient’s muscle strength improves after the injection, it can be a sign of MG.
Overall, diagnosing MG requires a combination of physical examination, blood tests, nerve conduction studies, SFEMGs, and tensilon tests. All of these tests can help the doctor confirm a diagnosis and rule out other conditions with similar symptoms.