Hemolysis is a process in which red blood cells are broken down, and can cause a variety of laboratory test results to be inaccurate or unreliable.
What is Hemolysis?
Hemolysis is the breakdown of red blood cells (RBCs). It occurs when RBCs are exposed to certain conditions, such as extreme temperatures, mechanical trauma, or certain chemicals. Hemolysis can cause a variety of laboratory test results to be inaccurate or unreliable.
How does Hemolysis Affect Test Results?
Hemolysis can affect a variety of laboratory tests, including complete blood count (CBC), electrolyte tests, liver function tests, and renal function tests. Hemolysis can cause an abnormally low hemoglobin or hematocrit, as well as elevated levels of potassium, lactate dehydrogenase (LDH), and bilirubin. It can also cause falsely elevated results in tests for glucose, calcium, chloride, and phosphorus.
How Can Hemolysis be Avoided?
Hemolysis can be prevented by collecting and handling blood samples correctly. The sample should be collected in a vessel that is specifically designed for collecting blood samples and is not made of glass. The sample should also be collected and transferred to the laboratory as quickly as possible, to avoid exposure to extreme temperatures or mechanical trauma. Additionally, the sample should be processed immediately upon arrival in the laboratory.
Hemolysis can have a significant impact on laboratory test results. It is important to take necessary precautions to ensure that samples are collected and handled properly to avoid hemolysis and inaccurate results.