Testing for Aspergillus in the body involves a variety of different diagnostic methods, which can be used alone or in combination depending on the clinical context.
If a physician suspects that a patient may have an Aspergillus infection, they will typically begin by performing a physical exam and taking a medical history. During the physical exam, the physician may look for signs of infection, such as skin lesions, redness, swelling, or other abnormalities. They may also order a chest X-ray or CT scan to evaluate the lungs and check for signs of infection.
The next step in diagnosing an Aspergillus infection is to take a sample of the affected tissue or fluid for laboratory testing. This can involve collecting a nasal swab, a bronchial lavage sample, or a sample of sputum or other fluids from the lungs. These samples can then be analyzed for the presence of Aspergillus fungi or its antigens.
In some cases, a skin or blood test may be used to detect antibodies against Aspergillus. These tests can be helpful in confirming an Aspergillus infection, but they are not always reliable, as some people may not have detectable levels of antibodies.
Finally, a biopsy may be used to collect a sample of tissue for analysis. This is typically done when other tests have not been able to confirm an Aspergillus infection or when the infection is in a difficult-to-reach area.
No single test is definitive for diagnosing an Aspergillus infection, and a combination of tests is often used to ensure an accurate diagnosis. It is important to speak to a doctor or other healthcare provider for advice on the best tests to use for diagnosing an Aspergillus infection.