Aspergillosis is a fungal infection caused by a type of mold called Aspergillus. It can cause a range of health problems, including lung infections, sinus infections, and skin infections. Testing for aspergillosis requires a combination of clinical, laboratory, and imaging tests.
The first step in testing for aspergillosis is a physical exam and a review of a patient's medical history. During the physical exam, a doctor will look for signs of infection, such as redness, swelling, or discharge. They will also ask questions about any allergies, exposure to mold, or other risk factors.
The next step is to order laboratory tests, such as a blood test, a sputum test, and a urine test. The blood test will look for antibodies to Aspergillus, which are produced by the body in response to the infection. The sputum test will look for fungal spores in the sputum, and the urine test will look for fungal metabolites in the urine.
In addition to laboratory tests, imaging tests may also be used to diagnose aspergillosis. Chest x-rays and computed tomography (CT) scans can be used to look for signs of infection in the lungs. Magnetic resonance imaging (MRI) and positron emission tomography (PET) scans can be used to look for signs of infection in other parts of the body.
Finally, a tissue sample may be taken from an infected area and examined under a microscope. This is called a biopsy. The doctor will be able to see the fungal spores and identify the type of Aspergillus causing the infection.
Testing for aspergillosis requires a combination of clinical, laboratory, and imaging tests. A physical exam and review of the patient's medical history are the first steps, followed by laboratory tests and imaging tests. A biopsy may also be needed to confirm the diagnosis.