Physical Examination
The first step in diagnosing a bone marrow disease is to perform a physical examination. During this exam, the doctor will check for signs such as fever, paleness, and swollen lymph nodes. Additionally, the doctor may take a sample of blood or bone marrow to analyze.
Laboratory Tests
The doctor may also order laboratory tests such as a complete blood count (CBC), a peripheral blood smear, and a bone marrow biopsy. A CBC will measure the number of red and white blood cells, as well as platelets. A peripheral blood smear will look at the shape and size of the cells, while a bone marrow biopsy will allow the doctor to obtain a sample of the bone marrow for further analysis.
Imaging Tests
Imaging tests may also be ordered to get a better look at the structure of the bone marrow and surrounding tissues. An X-ray, CT scan, or MRI can help the doctor determine if there is an abnormality in the bone marrow.
Genetic Testing
In some cases, the doctor may also order genetic testing to look for mutations in the DNA that may be associated with a bone marrow disease.
Treatment
Treatment of bone marrow disease will depend on the type and severity of the condition. Common treatments include transfusions, medications, and even surgery.