T-cell lymphoma is a type of non-Hodgkin's lymphoma (NHL) that affects the T-cells, a type of white blood cell that plays an important role in the immune system. T-cell lymphomas are typically aggressive and can spread quickly throughout the body. The outlook for people diagnosed with T-cell lymphomas depends on the type, stage, and treatment options available.
Types of T-Cell Lymphoma
T-cell lymphomas are classified into two main types: aggressive and indolent. Aggressive T-cell lymphomas are fast-growing, while indolent T-cell lymphomas are slow-growing. Some of the most common types of T-cell lymphomas include:
• Peripheral T-cell lymphoma (PTCL): PTCL is an aggressive type of T-cell lymphoma that typically affects the lymph nodes, but can also spread to other organs.
• Cutaneous T-cell lymphoma (CTCL): CTCL is a type of T-cell lymphoma that affects the skin and can cause an itchy rash.
• Anaplastic large cell lymphoma (ALCL): ALCL is an aggressive type of T-cell lymphoma that is typically found in the lymph nodes, spleen, or other organs.
Stages of T-Cell Lymphoma
T-cell lymphomas are typically staged using the Ann-Arbor staging system, which provides an estimate of the extent of disease based on the number of lymph nodes affected. T-cell lymphomas can be divided into four stages, from stage I (least advanced) to stage IV (most advanced).
Treatment Options for T-Cell Lymphoma
Treatment for T-cell lymphoma depends on the type and stage of the disease. Treatment options may include chemotherapy, radiation therapy, stem cell transplants, and targeted therapies. For some types of T-cell lymphoma, surgery may also be used to remove affected lymph nodes.
How Curable is T-Cell Lymphoma?
The outlook for people diagnosed with T-cell lymphomas depends on the type, stage, and treatment options available. Most people with aggressive T-cell lymphomas respond well to treatment, but may need to undergo multiple courses of treatment to keep the disease under control. In general, the prognosis for T-cell lymphoma is better than for other types of NHL.