Hemolysis, or the breakdown of red blood cells, can have an effect on the results of a complete blood count (CBC). A CBC is a routine blood test that measures the number of red blood cells, white blood cells, and platelets in the blood. Hemolysis can interfere with the accuracy of the CBC results, especially if the hemolysis is severe. In this article, we will discuss how hemolysis can affect the CBC results and what should be done if hemolysis is suspected.
What Is Hemolysis?
Hemolysis is the breakdown of red blood cells. It can be caused by a variety of factors, including physical trauma or mechanical damage to the cells, certain medications, infections, or autoimmune diseases. Depending on the cause, hemolysis can be acute or chronic.
How Does Hemolysis Affect CBC Results?
Hemolysis can interfere with the accuracy of the CBC results. If the hemolysis is severe, the red blood cell count may be falsely low. This is because the hemolyzed red blood cells are not counted as part of the CBC. Additionally, the hemolyzed red blood cells will release their hemoglobin, which can interfere with the accurate measurement of the hemoglobin concentration in the blood.
What Should Be Done If Hemolysis Is Suspected?
If hemolysis is suspected, it is important to take steps to prevent further hemolysis. This may include avoiding physical trauma to the blood sample or changing the handling of the sample. Additionally, the sample should be analyzed as soon as possible to prevent further hemolysis. Finally, if the CBC results are affected by hemolysis, the healthcare provider should be notified.