Angelman Syndrome (AS) is a rare genetic disorder that affects an individual’s intellectual and developmental capabilities. AS is caused by a mutation or deletion of the UBE3A gene, which is responsible for producing a protein that is essential for proper brain development. As a result, individuals with AS have impaired intellectual and cognitive abilities, as well as difficulties with speech and language.
IQ is a measure of a person’s intelligence and is used to evaluate intellectual functioning. Generally, individuals with AS experience a significant decrease in IQ scores. Studies have reported that the average IQ of individuals with AS ranges from 20 to 70, with the majority of individuals falling in the range of 25 to 55. This range is significantly lower than the average IQ of 100 in the general population.
In addition to lower IQ scores, individuals with AS often experience other cognitive deficits. These deficits may include difficulty with problem-solving, learning new information, and executive functioning. Many individuals with AS are unable to live independently or complete basic daily living tasks, such as dressing or eating, without assistance.
Individuals with AS also often experience social and behavioral difficulties. These may include difficulties interacting with peers, difficulty expressing themselves, and a tendency to engage in repetitive behaviors.
In summary, Angelman Syndrome does affect IQ. Individuals with AS have significantly lower IQ scores than the average population, and they often experience other cognitive deficits. Additionally, individuals with AS often experience social and behavioral difficulties that can significantly impact their quality of life.