Swyer Syndrome, also known as 46,XY Complete Gonadal Dysgenesis, is a genetic disorder that affects sexual development in genetic males. People with Swyer Syndrome typically do not develop testes, as they lack the genetic code necessary for them to develop.
Swyer Syndrome is caused by a mutation in the SRY gene, which is responsible for determining the development of male sex characteristics. As this gene is absent in people with Swyer Syndrome, they do not develop the same male reproductive characteristics that typical males do. This causes the testes to not develop, making it impossible for people with Swyer Syndrome to produce sperm or hormones.
People with Swyer Syndrome can still develop other physical characteristics that are typically associated with males, such as facial and body hair, a deepened voice, and a strong male-like skeletal structure. However, due to the lack of testes, they are unable to reproduce naturally.
People with Swyer Syndrome can still have children through the use of assisted reproductive technology, such as in-vitro fertilization. In cases where the person with Swyer Syndrome has a partner of the opposite sex, they can use donor sperm to fertilize the partner's egg, and then implant the embryo into the partner's uterus.
In cases where the person with Swyer Syndrome does not have a partner, they can use donor sperm and donor eggs to create an embryo, which can then be implanted into a gestational carrier. This allows the person with Swyer Syndrome to still have a biological child, even without the presence of testes.
In conclusion, people with Swyer Syndrome do not have testes. This is due to a mutation in the SRY gene, which prevents the development of male reproductive characteristics. While this does make it impossible for people with Swyer Syndrome to reproduce naturally, they can still have children through assisted reproductive technology such as in-vitro fertilization or donor sperm and egg.