Ankylosing spondylitis (AS) is a chronic, inflammatory type of arthritis that primarily affects the spine. Although it can cause pain and stiffness in other areas of the body, such as the hips, shoulders, and ribs, AS usually affects the back. While the exact cause of AS is still unknown, it is believed to be an autoimmune disorder triggered by a combination of genetic and environmental factors.
Blood tests are often used to help diagnose AS. However, it is important to note that a negative blood test does not necessarily rule out a diagnosis of AS. While certain blood tests, such as the Erythrocyte Sedimentation Rate (ESR) or C-reactive Protein (CRP) tests, can be useful in helping to diagnose AS, they are not definitive. Therefore, if a person has symptoms of AS but a negative blood test, other tests may be required to make a diagnosis.
Imaging Tests
Imaging tests, such as X-rays, CT scans, and MRI scans, can also be used to help diagnose AS. These tests can detect inflammation in the spine and other joints, as well as any changes in the bones, which can be indicative of AS. While imaging tests cannot definitively diagnose AS, they can help support a diagnosis.
Physical Exam
In addition to imaging tests and blood tests, a physical exam is also important for diagnosing AS. During a physical exam, the doctor may check for signs of inflammation, such as redness, warmth, and swelling, as well as for tenderness in the spine and other affected areas. The doctor may also check for any deformities, such as a “stiff spine” or fusion of the vertebrae.
Conclusion
In conclusion, a negative blood test does not necessarily rule out a diagnosis of ankylosing spondylitis. Other tests, such as imaging tests and physical exams, may be required to make a diagnosis. It is important to speak to your doctor if you have symptoms of AS, as early diagnosis and treatment can help prevent further complications.