Autoimmune hepatitis (AIH) is a chronic inflammatory liver disease caused by an autoimmune disorder. It occurs when the body’s immune system mistakenly attacks the healthy cells of the liver and causes inflammation. In severe cases, AIH can progress to cirrhosis, a condition in which the liver is severely damaged and scarred.
The risk of AIH progressing to cirrhosis depends on the severity of the disease, the length of time it has been left untreated, and the effectiveness of the treatment. In some cases, AIH can progress to cirrhosis after several years of persistent inflammation of the liver.
In general, AIH is a treatable condition. Early diagnosis and prompt treatment are important for slowing the progression of the disease and preventing it from worsening. Treatment often includes immunosuppressive drugs, which help to reduce inflammation and prevent further damage to the liver. Corticosteroids and azathioprine are two commonly used medications. In some cases, a liver transplant may be necessary to treat AIH.
Cirrhosis is a serious and potentially life-threatening condition that can develop as a result of AIH. If left untreated, AIH can lead to cirrhosis, which can cause serious complications such as liver failure, jaundice, and an increased risk of liver cancer. Therefore, it is important for those with AIH to receive prompt and effective treatment to reduce their risk of developing cirrhosis.